Anemia with normal iron levels,

Anemia with normal iron levels, Traducere "an iron deficiency anemia" în română

The presence of anemia, regardless of the cause or mechanism, in oncologic patients adversely affects the quality of life, the outcome of the neoplastic disease and the adherence to treatment. The mechanisms involved in the appearance of anemia in oncologic patients are intricated.

Medicul mi-a spus Am un deficit de fier. Exces de potasiu, deficientă de fiertoate sunt evidente medicale. It's a supplement for an iron deficiency.

Iron deficiency is a frequent cause of anemia in oncologic patients. In oncologic patients, the pre­va­lent mechanism for iron deficiency is the functional mechanism.

an iron deficiency anemia - Traducere în română - exemple în engleză | Reverso Context

In this case, the iron stores are reduced due to the underlying oncologic condition or due to inflammatory processes associated to cancer treatments. Iron deficiency in cancer patients is often underestimated, mainly due to the difficulty of defining iron deficiency on the basis of usual laboratory markers.

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The current therapeutic options of cancer anemia include blood transfusions, iron substitution and erythropoietin-stimulating agents. Keywords cancer anemia, iron deficiency, anemia treatment Rezumat Anemia este o complicaţie frecventă la pacienţii oncologici, fiind întâlnită atât la momentul diagnosticului, cât şi în cursul terapiilor oncologice.

Prezenţa anemiei, indiferent de cau­ză, la pacienţii oncologici are un impact negativ asupra ca­li­tă­ţii vieţii, a prognosticului bolii şi a aderenţei la tratament.

Iron deficiency and cancer – clinical implications

Me­ca­nis­mele de producere a anemiei la pacienţii oncologici sunt multiple, putând fi determinată de malabsorbţie şi mal­nu­tri­ţie, sângerare acută sau cronică, inflamaţie sistemică, in­fil­tra­re metastatică a măduvei osoase şi de mielosupresie se­cun­da­ră tratamentului.

Deficitul de fier la pacienţii cu can­cer este una dintre cele mai frecvente cauze de anemie.

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Este în­tâl­nit la aproape jumătate din pacienţii cu tumori solide şi he­ma­to­lo­gice. La pacienţii cu boală oncologică, mecanismul pre­do­mi­nant al deficitului de fier este cel funcţional, disponibilitatea fie­ru­lui fiind redusă din cauza bolii sau a proceselor inflamatorii le­ga­te de terapie.

Traducere "iron deficiency" în română

Deficitul de fier la pacienţii cu cancer ră­mâ­ne adesea subevaluat, în mare parte din cauza dificultăţii de­fi­ni­rii acestuia pe baza markerilor de laborator uzuali. Op­ţiu­ni­le terapeutice actuale ale anemiei din cancer includ trans­fu­zii­le de sânge, substituţia cu fier şi agenţii de stimulare anemia with normal iron levels eri­tro­po­ie­ti­nei. Cuvinte cheie anemia în cancer deficit de fier terapia anemiei Introduction Anemia is a frequent complication in cancer patients, both with solid and haematological tumors, and negatively influences the quality of life, the performance status and the prognosis of these patients.

Jern mangel anemi - este cea mai frecventa forma de anemie. The blood becomes iron 'poor' and iron deficiency anemia may develop. Sângele devine de fier "săraci" și anemia feripriva se poate dezvolta. The risk factors for iron-deficiency anemia are: Factorii de risc pentru anemia cu deficiență de fier sunt: The symptoms of mild iron-deficiency anemia may be unnoticed. Simptomele anemiei cu deficiență de fier nu sunt observate.

It is important to recognise this condition rapidly and to manage and treat it, and consequently to improve the quality of life, the tolerability and adherence to cito­toxic treatment and the response to oncologic treat­ments.

The data available show that the frequency of anemia in cancer patients is very high. The increased incidence of anemia in oncologic patients is associated with the type of oncologic disease, the advanced stage of the disease and previous treatments.

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As for the type of disease, anemia is more common in haematological diseases compared to solid tumors. In solid neoplasia, anemia is commonly anemia with normal iron levels with bronchopulmonary, breast, gastrointestinal and gyne­cological cancers 2,3.

Mechanisms involved in anemia and iron deficiency in oncologic patients The mechanisms involved in the occurrence of anemia in cancer patients are multiple and complicated, with several mechanisms responsible for anemia occurring at the same time or at different times 4.

Plasma Transferrin

By reviewing the most important mechanisms of anemia, these may be acute or chronic bleeding, commonly found anemia with normal iron levels gynecological tumors and digestive tract. The nutritional deficiencies of iron, vitamin B12 and folate, determined by malnutrition or malabsorption, anemia with normal iron levels other common causes of anemia in these patients.

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Bone marrow infiltration by metastatic disease is frequently found in patients with anemia and breast or prostate cancer. Other causes in patients with neoplastic disease is the decline in the production of endogenous erythropoietin, seen in patients with cancer and associated chronic renal disease, or due to decreased response to bone marrow erythropoietin 2,5,6.

  • Traducere "iron deficiency" în română Iron in kidney and heart failure: from theory to practice.
  • На какие-то секунды он забылся в старой, привычной мечте: он вообразил, что небо подвластно ему, что, распростершись, мир лежит под ним, приглашая отправиться туда, куда ему хочется.

  • Iron in kidney and heart failure: from theory to practice.

In terms of iron deficiency, it is classified into two types — absolute and functional. Absolute deficiency appears when the iron storage are low and depleted. Functional deficiency is present when iron reserve is normal or increased, but the disponibility of iron for erythropoiesis is low due to inflammatory processes that cause iron blocking in macrophages anemia with normal iron levels enterocytes.

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [ Having the magnitude of epidemics, anemia is a global public health problem, which affects both the emerging countries and the developed ones, with major consequences for human health and for social and economic development.

The mechanism of functional iron deficiency in cancer patients is well known. Iron is taken by the transferrin from duodenal enterocytes or macro­phages that recycle the iron from aging erythrocytes and it is transported to the bone marrow 8.

These mechanisms are controlled by hepcidin, which is an amino acid produced in the liver by peptic hepcidin anti-microbial genes at chromosome 19, in the pre­sence of anemia with normal iron levels or chemotherapy-induced inflam­mation.

Hepicidin has oxiuros gases role of maintaining iron homeostasis 9. Hepcidin block the release of iron from the macrophages in the bone marrow by blocking ferroportin, which has the role to transfer the iron from the gastric mucosa to the transferrin.

Iron in kidney and heart failure: from theory to practice.

The functional deficiency of iron occurs following the release of cytokines, especially inter­leukin-6, in the presence of inflammation, which results in hepcidin production increased in the liver. High levels of hepcidin are found in many types of hematological and solid cancers.

Low levels of hepcidin have been observed in patients with hepatic metastases Evaluation of patients with anemia and iron deficiency Iron deficiency in cancer patients is a common state. But it is very difficult to recognize it. Evaluating the profile of patients with iron deficiency, data available from studies show that patients with tumors of the colon, rectum, pancreas and pulmonary syndrome have a very frequent iron deficiency.

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