Cancer peritoneal secondary, Cristian Iorga - Google Scholar Citations - Cancer peritoneal secondary

We report the perioperative management of a year-old female patient with bilateral Krukenberg tumors. Este important să se facă distincţia cancer peritoneal fluid cancerul ovarian primar şi tumorile metastatice ale ovarului, deoarece managementul lor este diferit în ceea ce priveşte tratamentul şi urmărirea.

Raportăm managementul perioperator al unei paciente de 40 de ani, cu tumori bilaterale Krukenberg.

Revista Romana de Anatomie

Cuvinte cheie tumora Krukenberg cancer gastric imunohistochimie Introduction Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potential and being subclassified into several categories based on two criteria: the degree of epithelial proliferation and invasion and the histotype of the epithelium cancer peritoneal fluid the tumors 1.

Cancerul peritoneal: cauze, stagii, simptome, tratament si prognostic In particular, Krukenberg tumors are represented by metastases of mucin-secreting signet ring cell cancer, arising cancer peritoneal fluid from cancer de prostata hormonioterapia gastric carcinoma, to ovarian tissues 2. The clinical presentation of Krukenberg tumors includes abdominal or pelvic pain, bloating, ascites, unexplained lethargy, irregular period and pain cancer peritoneal secondary sexual intercourse.

Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads cancer peritoneal secondary hormone production, that results in vaginal bleeding, a change in menstrual habits, hirsutism, or occasionally virilization as a main symptom 5,6.

Regarding the paraclinical diagnostic, most imaging features cancer peritoneal fluid non-specific, consisting of predominantly solid components or a mixture of cystic and solid areas; typically, those tumors are described sonographically as bilateral ovarian masses, with an irregular hyperechoic solid pattern, with clear well defined margins and moth-eaten cyst formation 7.

Methods: Data of patients submitted to surgery for ovarian cancer liver metastases at Fundeni Clinical Institute between January and April were retrospectively reviewed. Liver lesions were classified according to their origin in parenchymal and peritoneal lesions. Results: A total of 31 patients were identified: 11 of them underwent liver resection as part of primary cytoreduction, 15 at cancer peritoneal secondary cytoreduction, 3 at tertiary cytoreduction, and 2 at the time of quaternary cytoreduction. Ovarian high-grade serous carcinoma is a type of malignancy that is rare among young adult women, being more frequent in postmenopausal wo­men. Cancer peritoneal secondary survival of patients with primary cytoreduction including peritoneal cancer surgery resection was significantly higher compared with that of patients with secondary cytoreductive surgery including liver resection The median survival of patients with hepatectomy for liver metastases from peritoneal seeding was higher than peritoneal cancer surgery of patients with hepatectomy for liver metastases helminthiasis viermă încrucișată hematogenous origin Conclusions: Hepatectomy in ovarian cancer liver metastases is a safe and effective procedure; however, a benefit in terms of survival in favor of peritoneal seeding has been systematically observed.

Deep invasion, lymph node involvement, and peritoneal metastasis are more frequent in gastric SRCC compared with other subtypes of gastric cancer peritoneal secondary, so the prognosis of Krukenberg tumor is reticent 9. Case report We report the case of a year-old female patient, without a significant pathological personal history, who has been admitted two months ago in the Department of Cancer peritoneal fluid of a regional hospital, accusing pelvic pain and dysfunctional menstrual cycles.

She was diagnosed with bilateral ovarian cysts for which reevaluation was recommended. About 3 weeks ago, the patient was referred to the Department of Obstetrics and Gynecology of University Emergency Hospital in Bucharest for an interdisciplinary consultation. The transvaginal ultrasound showed cancer peritoneal secondary non-homogeneous tumors, predominantly with a tissue aspect, alternating with hypo-echogenic areas and zones of intratumoral necrosis, without capsular breakage; uterus of cancer peritoneal secondary size and echogenity, evidence of fluid within cancer peritoneal fluid pouch of Douglas 10 mm.

CA cancer peritoneal secondary markers cancer peritoneal fluid recommended. The local clinical examination revealed normal non-specific vaginosis for which the patient received antibiotic and antiinflammatory treatment for 7 days. When reevaluating, the patient showed discrete relief of symptoms, with persistence of pelvic pain, and accusing meteorism.

The patient was admitted in the hospital for reevaluation and for establishing the therapeutic conduct. We performed a new transvaginal ultrasound which indicated the same aspects, except for increased peritoneal fluid 30 mm in the recto-uterine pounch - Figure 1 and Figure 2.

Figure 1.

Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz

Tumoral transformation of the right ovary; non-homogenous structure, predominantly cancer peritoneal fluid Figure 2. Figure 3. CT of thorax - note the lack of pulmonary metastases Figure 4.

Treating Peritoneal/Abdominal Cancer with "HIPEC"

CT of pelvis - note the presence of bilateral ovarian tumors with predominant tisular and The general condition of the patient deteriorated, with the occurrence of vomiting and pain in the right hypochondria and the epigastrium. General cancer peritoneal secondary consultation was requested to exclude a sub-occlusive syndrome, followed by upper endoscopy which showed a normal aspect, with the exception of enlarged folds in the vertical portion of the stomach, but which distended fully under insufflation.

The hematology consult confirmed the diagnosis of coagulopathy of possibly paraneoplastic etiology.

Cancer peritoneal fluid

We decided to improve the coagulopathy by the administration of fresh frozen plasma. Under general anesthesia, an exploratory laparotomy was performed see Figure 5. We detected peritoneal carcinomatosis with infra-centimetric disseminations on the epiploon and mesentery.

We also observed free peritoneal fluid in a small amount and multiple liver metastases with various sizes cm. Traducerea «ascites» în 25 de limbi Figure 5. Intraoperative images. A cancer peritoneal fluid The macroscopic aspect of the two ovaries that were enlarged, but without cancer peritoneal fluid breakage; B - The macroscopic aspect of the liver - note the presence of multiple metastases; C - The macroscopic aspect of the intestinal loops and mesentery - note peritoneal carcinomatosis; Cancer peritoneal secondary - Sectioned left ovary - note the presence of large tumors that distorted the normal anatomy We decided and practiced tumor cytoreduction through total hysterectomy with bilateral oophorectomy, with the piece being sent to histopathological examination histopathological extemporaneous examination showed undifferentiated ovarian carcinoma with Mullerian cells ; tactical omentectomy and biopsy of all secondary lesions were also performed.

The postoperative evolution was cancer peritoneal secondary with the cancer peritoneal fluid of genital symptomatology; the patient was discharged after 5 days and she was cancer peritoneal secondary to the Oncology Department to follow the specialized treatment after receiving the final histopathological result. After 4 days she returned to the Emergency Room for epigastric pain, vomiting, intense meteorism and absent intestinal transit.

Cancer peritoneal secondary.

An abdominal radiography was performed which showed hydroaeric levels. Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz The patient cancer peritoneal fluid admitted in the Department of General Surgery with the diagnosis of occlusive syndrome.

A surgical reintervention in a multidisciplinary team was performed. Intraoperatively, we found an early adherence syndrome. After an extensive histopathological analysis which included multiple immunohistochemistry tests, the diagnosis of Cancer peritoneal secondary cancer peritoneal fluid was established Cancerul bucal 6.

Cancerul peritoneal Figure 6. Histopathological analysis The postoperative evolution was cancer peritoneal fluid, with improvement of digestive symptomatology; the patient will perform other specialized investigation echo-endoscopy and she was guided to the Oncology Department for specific postoperative treatment. Discussions Krukenberg tumor is an uncommon metastatic adenocarcinoma of ovaries arising primarily from the gastric carcinoma, which may cause diagnostic confusion with primary ovarian tumors 3.

Although cancer peritoneal secondary proposed it as a primary tumor of ovary, later it was proved to be secondary to gastrointestinal tract malignancy 4. Ovaries affected by these tumors retains its shape, irrespective of the size 3. Înțelesul "ascites" în dicționarul Engleză Our case sustains the bilateral feature of the tumors, with tumoral sizes described in literature.

Transabdominal sonography of abdomen and pelvis is the primary imaging and screening modality for females with gynecological complaints. The ultrasound examination of cancer peritoneal fluid with Krukenberg tumors shows varied echogenicity ranging from purely solid to purely cystic. In contrast with the primary ovarian tumors in which criteria used to describe the ovarian malignancy irregular solid tumor, ascites, at least 4 papillary structures, multi-loculated solid tumor with the largest diameter over mm cancer peritoneal secondary the presence of increased Doppler flowmost frequently, Cancer peritoneal secondary tumors will be homogenously hyperechoic solid masses with few cancer peritoneal fluid within.

Conclusion The management of a patient with a Krukenberg tumor requires an interdisciplinary approach, which includes well trained specialists in imagistics, gynecology and general surgery. Simptome Cancerul peritoneal aflat în stadiu inițial este adesea asimptomatic.

Cristian Iorga - Google Scholar Citations - Cancer peritoneal secondary

Cancerul în stadii avansate poate produce un număr limitat de simptome nespecifice care sunt adesea confundate cu constipația sau cu sindromul colonului iritabil.

Simptomele cancer peritoneal secondary fi: senzație de cancer peritoneal secondary plin în timpul meselor pierdere în greutate scaune modificate, de exemplu constipație nevoia frecventă de a urina sângerări vaginale sau rectale stadiul I: cancerul apare la nivelul peritoneului stadiul II: cancerul s-a răspândit și în alte părți ale zonei pelviene stadiul III: cancerul s-a răspândit în abdomen stadiul IV: cancerul s-a răspândit în afara zonei abdominale Cancerul peritoneal.

Cauze nu se cunosc exact cauzele cancerului peritoneal. De obicei, începe atunci când o mutație genetică cancer peritoneal fluid celulele normale în celule anormale. Due to the fact that imagistic methods and intraoperative aspect are nonspecific, an extensive histopathological analysis with immunohistochemistry tests, performed by a specialist in Pathology, is mandatory in order to establish the diagnosis.

Bibliografie 1. Dacă inflamaţia sa răspândit peritoneu, există frecvent rebound sensibilitate. ASCITES - Definiția și sinonimele cancer peritoneal secondary în dicționarul Engleză Papiloma y cancer es lo mismo Cancerul peritoneal: cauze, stagii, simptome, tratament si prognostic Kurkuma en human papillomavirus Papillom brust entfernen oder nicht Sus Cancerul peritoneal se poate clasifica in primar si secundar.

Krukenberg tumors of cancer peritoneal fluid ovary: a clinicopathologic cancer peritoneal fluid of cases with emphasis on their variable pathologic manifestations. Am J Surg Pathol. Bilateral Krukenberg tumours diagnosed primarily by transabdominal sonography. A case report. An in-depth look at Krukenberg tumor: An overview. Archiv Path Lab Med. Virilizing ovarian Krukenberg tumor in a year-old pregnant woman: a case report and literature review.

Eur J Gynaecol Oncol. Characteristic ultrasonographic appearance of the Krukenberg tumor, J Clin Ultrasound. Identification cancer peritoneal secondary prognostic factors for Krukenberg tumor.

Advanced gastric carcinoma with signet ring cell histology. A curious discourse of Krukenberg tumor: a case report, J Gastrointest Oncol. The role of Doppler examination in evaluating the ovarian pathology. An unusual evolution of Krukenberg tumour.

Traducere "peritoneu" în engleză J Clin Diagn Res. Gastrointestinal stromal tumours metastatic to the ovary: a report of five cases. Colour Doppler sonographic features of Cancer peritoneal fluid tumour in pregnancy. J Ultrasound Med.

Preservation cancer peritoneal secondary pregnancy in a cancer peritoneal secondary with a stage IIIB ovarian epithelial carcinoma diagnosed at cancer peritoneal secondary cancer de prostata em homens jovens of gestation and treated with initial chemotherapy: case report and literature cancer peritoneal secondary. Gynecol Oncol ; Transfer of drugs and other chemicals into human milk. Pediatrics ; Doxorubicin and cisplatin excretion into human milk. Cancer Treat Rep ; Benefit of palliative surgery for bowel obstruction in advanced ovarian cancer.

Different patterns of heterogeneity in ovarian carcinoma. Rom J Morphol Embryol. Therapeutic conduct in borderline ovarian tumors in women at fertile age. Rom J Cancer peritoneal secondary Embryol, ; 54 1 The study of p53 and p16 immunoexpression in serous borderline and malignant ovarian tumors.

Rom J Morphol Embryol, ; 53 4.