metastatic colorectal cancer - Traducere în română - exemple în engleză | Reverso Context

Metastatic cancer no treatment

Aggressive variants of prostate cancer - Are we ready to apply specific treatment right now?

Cancer Treat Rev. In most cases, prostate cancer essentially depends on androgen receptor signaling axis, even in castration-resistant setting, and hence may be targeted by second generation hormonal therapy. However, a subset of patients bears androgen-independent cancer biology with a short-term response to hormonal treatment, early and extensive visceral metastases, low PSA levels and poor outcomes.

metastatic cancer no treatment

Identification and specific management of these rapidly metastatic cancer no treatment malignancies is of an unmet medical need since their classification and utilized therapeutic regimens vary significantly.

Unfortunately, molecular pathways have not been sufficiently elucidated yet in order to provide an effective targeted treatment with a prolonged response.

Female Urethral Carcinoma The female urethra is largely contained within the anterior vaginal wall. In the adult it is 2 to 4 cm in length. Distally, it is lined with stratified squamous epithelium, changing to stratified or pseudostratified columnar metastatic cancer no treatment more proximally.

Lack of diagnostic and predictive biomarkers for these cancers makes successful counteractions against them even more sophisticated. In this comprehensive review, we aimed at summarizing the current body of literature reporting on causal molecular machinery as well as diagnostic and therapeutic concepts metastatic cancer no treatment aggressive prostate tumors and draw clinically relevant conclusions for the up-to-date sensible disease management. Int J Mol Sci.

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  2. Traducere "metastatic colorectal cancer" în română, Metastatic cancer no treatment

Attention is accorded to their potential in anti-cancer therapies as single agents or adjuvant treatment. Herby, we evaluated the in vitro effects of a panel of natural compounds with focus on caffeic acid phenethyl ester CAPE and Kaempferol for the treatment of human colon cancer. Modifications in gene expression were investigated through microarray and detection of existing mutations and finding of new ones was done with the help of Next Generation Sequencing NGS.

Romania Cancer Oranisations and Resources | CancerIndex

Moreover, there are pathogenic mutations that are no longer found upon treatment metastatic cancer no treatment CAPE and Kaempferol.

Chirurgia Bucur. In Romania, surgery was at the forefront of therapeutic options. Nevertheless, current data shows that in fact, a large number of patients are still referred to surgery in various stages of diagnosis and treatment.

It was noted that recommendations may differ, in spite of the wide dissemination of the literature data. Works published so far, discussing the role of surgery in LACC treatment shows a lack of consensus. On top of that, late enrolement to RT and low acces to specialized centers metastatic cancer no treatment the problem. Performing surgery not only allows the evaluation of the pathological response to chemo-radiotherapy, but also achieves a better local control.

Carcinoma of the Urethra - Holland-Frei Cancer Medicine - NCBI Bookshelf

In conclusion, there is still a place for surgery within locally advanced cervical cancer treatment options. More trials need to be carried out in order to confirm the findings and establish high levels of confidence for each piece of information provided.

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Several lines of evidence support the observation that polyphenols have preventive and therapeutic effects in prostate cancer. Moreover, prostate cancer is ideal for chemoprevention due to its long latency. We propose here an equilibrated lifestyle with a diet rich in polyphenols as prophylactic attempts to slow down the progression of localized prostate cancer or prevent the occurrence of the disease.

In metastatic cancer no treatment review, we will first summarize the molecular mechanisms of polyphenols metastatic cancer no treatment prostate cancer with a focus on the antioxidant and pro-oxidant effects, androgen receptors ARkey molecules involved in AR signaling and their transactivation pathways, cell cycle, apoptosis, angiogenesis, metastasis, genetic aspects, and epigenetic mechanisms. The relevance of the molecular mechanisms is discussed in light of current bioavailability data regarding the activity of polyphenols in prostate cancer.

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We also highlight strategies for improving the bioavailability of polyphenols. We hope that this review will lead to further research regarding the bioavailability and the role of polyphenols in prostate cancer prevention and treatment. Sunbed use legislation in Europe: assessment of current status. J Eur Acad Dermatol Venereol. Young women are the most frequent users, therefore, there is an increasing concern about the regulation of sunbed use.

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The questionnaire was sent to Euromelanoma coordinators and to designated coordinators out of the Euromelanoma network.

Roughly one-third of the countries does not have a restriction for minors. In the vast majority of cases, the number of licensed or closed tanning centres is unknown.