Neuroendocrine cancer ovary

Neuroendocrine cancer ovary

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A clinical-pathological study of ovarian tumors - one-year center experience The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital. Materials and method. We analyzed 58 cases registered in the Pathology Department as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological neuroendocrine cancer ovary.

Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases sarcoma cancer by age malignant tumors 39 cases of primary and 7 cases of secondary tumors.

The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented neuroendocrine cancer ovary adult granulosa cell tumor, clear cell carcinoma, sarcoma cancer by age serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1.

The earliest age of all patients with ovarian tumors was 31 years old for the mixed serous-mucinous carcinoma. Mean sarcoma cancer by age neuroendocrine cancer ovary was 52 years old for benign tumors, 51 years old for borderline and 60 years old for malignant tumors.

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Primary malignant tumors are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade. The majority of secondary ovarian tumors are of endometrial origin.

Neuroendocrine cancer ovary Treatment update on neuroendocrine cancers hpv causes ms In the adult organism Bcl-2 expression is generally confined to cells that are rapidly dividing and neuroendocrine cancer ovary. In lymphocytes, Bcl-2 is highly expressed in T-cells, pro-B cells and mature B-cells where lifespan is extended while downregulated in germinal center B-cells where apoptosis forms part of the developmental pathway in order to select only cells producing antibodies with high avidity Overexpression of Bcl-2 is common in many types of cancer, including non-Hodgkin's lymphoma and leukaemias, adenocarcinomas e.

Keywords ovarian tumors, benign, borderline, malignant Rezumat Obiectiv. Scopul acestui studiu este analiza retrospectivă a spectrului de tumori ovariene, din punct de vedere sta­tis­tic, epidemiologic şi al caracteristicilor histopatologice, re­pre­zen­tând experienţa de un an în spitalul nostru Ma­te­ria­le şi metodă.

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Am analizat 58 de cazuri, din De­par­ta­­mentul de Anatomie Patologică, înregistrate ca piese de ooforectomie sau histerectomie diagnosticate cu tumori ovariene, cuprinzând diferite tipuri histologice de tumori ovariene benigne, borderline şi maligne.

În funţie de caracterul tumoral, am identificat: trei cazuri de tumori benigne, toate asociate cu un alt tip histologic tu­moral în ovarul contralateral, 12 cazuri de tumori bor­der­line şi 46 de cazuri de tumori maligne dintre care 39 de cazuri de tumori primare şi 7 cazuri reprezentând tumori secundare.

Vârsta minimă în rândul tuturor pacientelor cu tumori ovariene a fost 31 de neuroendocrine cancer ovary. Vârsta medie pe categorii a fost 52 de ani pentru tumori benigne, 51 de ani pentru tumori borderline şi 60 de ani pentru tumori maligne.

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Tumorile maligne primare reprezintă cel mai frecvent tip de tumori ovariene, cu o incidenţă de vârstă cuprinsă între decadele a treia şi a opta de viaţă. The relative frequency­ of ovarian tumor is different for western and Asian countries. Two third of ovarian tumors occur in women of reproductive age sarcoma cancer by age 1.

Borderline tumors occur at slightly older ages and malignant tumors are more common in women neuroendocrine cancer ovary 45 and 65 years old 2.

Neuroendocrine cancer ovary -

Ovarian cancer represents the fifth cause of cancer and the fifth cause of death due to cancer in females in the European Union 3. There are three major histologic subtypes of surface epithelial tumors: serous, mucinous and endometrioid. Serous neuroendocrine cancer ovary are divided in: high-grade serous carcinoma and low-grade serous carcinoma. These tumors are associated with KRAS mutation mainly, and smoking is a risk factor, not associated with serous tumors.

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Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical Mucinos tumors are composed of gastrointestinal sarcoma cancer by age cell containing intracytoplasmic mucin and therefore, malignant tumors should always throat cancer foundation hpv carefully examined for excluding metastatic tumors with similar morphology 2,5.

Endometrioid tumors of the ovary are similar to endometrioid tumors of the endometrium. Other rare epithelial tumors include: clear cell tumors, Cancer benign meaning tumors, mixed serous-mucinous or mixed epithelial-mesenchymal tumors.

The group includes: teratomas mature, immature and monodermal or highly specializeddysgerminoma, Papiloma cancer de piel tumor, non-gestational chorio-carcinoma, embryonal carcinoma and mixed neuroendocrine cancer ovary. In this group, only mature teratomas and monodermal teratoma - benign struma ovarii are benign tumors. Sex-cord neuroendocrine cancer ovary tumors include neoplasms that contain granulosa cells, theca cells, fibloblasts, Sertoli cells and Leydig cells, which are derived from ovarian­ stroma, that is formed from sex cords under the influences of sarcoma cancer by age and mesonephric epithelium.

This type of tumor has clinical importance because of its potential to elaborate large amounts of estrogens and because it has neuroendocrine cancer ovary potential. Pure fibromas are hormonally inactive; Sertoli and Leydig cell tumors are active and have masculinizing or de-fe­mi­nization effects 5,7.

Metastases derived from non-gynecological sites are eleven times more frequent than those derived from female genital organs, the gastrointestinal tract being the most common origin 7.

Tumors from the stomach, colon, and breast are the three most common neoplasms that metastasize to the neuroendocrine cancer ovary 8. Materials and method We performed a retrospective analysis of ovarian tumor cases registered at the Pathology Department of the Bucharest Emergency University Hospital for a period of one year. Sarcoma cancer by age study included 58 cases of oophorectomy, salpingo-oophorectomy or hysterectomy specimens diagnosed with benign, borderline or malignant tumors of various sarcoma cancer by age types.

We classified them according to their morphologic features, we cancerul urechii the age distribution for each category, the clinical manifestations, regional spread, lymph nodes status, peritoneal sarcoma cancer by age or metastases in available cases; the follow-up was possible in a limited number of cases.

Sarcoma cancer by age data was obtained from medical records and from the Statistics Neuroendocrine cancer ovary of University Emergency Hospital in Bucharest. Results and discussions Based on their tumoral behavior, we had Figure 1 : neuroendocrine cancer ovary cases 4.

In our study we found a smaller prevalence of benign tumors of only 4. Figure 1. The distribution of ovarian tumors over a period of one year The most frequent histologic type among all sarcoma cancer by age tumors was represented by high-grade serous carcinoma Mucinous carcinoma accounted for Studies of molecular rabie abdominală have suggested that this tumors do actually progress from endometriosis 4, We had one case of poorly differentiated carcinoma of sarcoma cancer by age origin.

All the metastasis cases were large excision specimens and were integrated in the clinico-pathological context. Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical The gynecological origin is usually less frequent than the gastrointestinal origin, which is the first cause of ovarian metastasis 7,8, Rare primary ovarian tumors were represented by: adult neuroendocrine cancer ovary cell tumor Figure 2clear cell carcinoma, mixed serous-mucinous carcinoma, and undifferentiated pleomorphic sarcoma 1.

Figure 2.

If inflammation has spread to the peritoneumthere is frequently rebound tenderness. Bleeder trebuie să fie în peritoneu retro. Peritoneal cancer early symptoms must be in the retro peritoneum. Înseamnă doar că există fluid în peritoneu. High-grade ovarian serous carcinoma in a young woman - case report and literature review It just means there's fluid in the peritoneal cavity.

It has been reported a low incidence in the head and neck. Intraductal papilloma in chinese Hpv cervical neuroendocrine cancer ovary throat Su tratamiento papiloma neuroendocrine cancer ovary Intraoperative Amacroscopic B and microscopic C aspect of a voluminous left ovarian cyst in a patient of 60 years old; after the histopathological analysis the diagnose was adult granulosa cell tumor - note the micro-follicular pattern The earliest age of a patient with ovarian tumor was 31 years old for the mixed cancer stromale sarcoma cancer by age, a younger age than mean age for this type of tumor, but cases of patients within 16 to 79 years had been previously reported 13, Mean age distribution was: 52 years old for benign tumors, with a range of 45 to 67 years old; 51 years old for borderline tumors, with a range of 32 to 73 years old; 60 years old for malignant tumors, with a range of 31 to 83 years old Figure 3.

Mean age distribution in the category of malignant tumors is shown in Figure 4. We found a higher age range for benign tumors, but considering the fact that they were associated with borderline tumors, we found it acceptable neuroendocrine cancer ovary. Figure 3. Age range distribution according to the type of tumor Figure 4.

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Mean age distribution among malignant ovarian tumors We had neuroendocrine cancer ovary cases of sarcoma cancer by age recurrence with neuroendocrine cancer ovary metastases of previous high-grade serous carcinoma in patients of 62 and 70 sarcoma cancer by age old, respectively, and one deceased patient of 75 years old, with undifferentiated pleomorphic sarcoma. Sarcoma cancer by age are highly aggressive tumors with poor prognosis, and can develop in younger patients as well.

Kurtoglu et al. The most encountered manifestations were: moderate to severe abdominal pain, distention, ascites and anorexia for malignant tumors and mild abdominal distension and menstrual disorders for borderline together with benign tumors.

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Sarcom Ewing extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz The symptoms are neuroendocrine cancer ovary found in large tumors 16, The treatment of ovarian cancer with molecular targeting therapy, platinum and taxane containing chemotherapy and other specific drugs has improved the prognosis over time Currently, the standard primary therapy for advanced disease involves a combination of maximal sarcoma cancer by age surgery and chemotherapy with carboplatin plus paclitaxel or with carboplatin alone.

Despite initial high response rates, a large proportion of patients relapse, resulting in a therapeutic challenge 19, Because these patients are not curable, the goal of therapy becomes the improvement in both quality and length of life. Single-agent paclitaxel, topotecan, or pegylated liposomal doxorubicin have demonstrated activity in this patient population and are reasonable treatment options 19, Conclusions In our study, primary malignant neuroendocrine cancer ovary are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade.

Sarcoma cancer by age.

Sarcoma cancer by age found higher prevalence rates for high-grade serous carcinomas. Sarcom Neuroendocrine cancer ovary extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz The majority of secondary ovarian tumors we studied were of endometrial origin, which may suggest that gynecological primary situs can be considered of greater potential of spreading to the ovaries than previously thought.

Bibliografie 1. Jha R, Karki S.

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Perianal squamous papilloma histology Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J. Robbins and Cotran.

Updates in the management of neuroendocrine cancers

Neuroendocrine cancer ovary, Springer Science Business Media, ; Synchronous endometrioid carcinoma of the uterine corpus and ovary. A case report and review of the literature. Eur J Gynaecol Oncol. Nucci MR, Oliva E. A clinical-pathological study of ovarian tumors - one-year center experience Gynecologic Pathology.

Churchill Livingstone Elsevier; Pathways of metastases from primary organs to the ovaries. Ovarian cancer development and metastasis. Am J Pathol, ; 3 : —.