Ovarian cancer metastatic prognosis

It is important to distinguish between primary ovarian cancer and metastatic tumors in the ovary because their management is different, in terms of treatment and follow-up.

We report the perioperative management of a year-old female patient with bilateral Krukenberg tumors. Este important să se facă distincţia între cancerul ovarian primar şi tumorile metastatice ale ovarului, deoarece managementul lor este diferit în ceea ce priveşte tratamentul şi urmărirea.

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Raportăm managementul perioperator al unei paciente de 40 de ani, cu tumori bilaterale Krukenberg. Cuvinte cheie tumora Krukenberg cancer gastric imunohistochimie Introduction Ovarian cancer metastatic prognosis tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potential and being subclassified into several categories based on two criteria: the degree of epithelial proliferation and invasion and the histotype of the epithelium composing the tumors 1.

In particular, Krukenberg tumors are represented ovarian cancer metastatic prognosis metastases of mucin-secreting signet ring cell cancer, arising primarily from the gastric carcinoma, to ovarian tissues 2.

Profilul de risc clinic asociat cancerului ovarian

The clinical presentation of Krukenberg tumors includes abdominal or pelvic ovarian cancer metastatic prognosis, bloating, ascites, unexplained lethargy, irregular period and pain during sexual intercourse. Perioperative management of a patient with Krukenberg tumor - a case report Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in vaginal bleeding, a change in menstrual ovarian cancer metastatic prognosis, hirsutism, or occasionally virilization as a main symptom 5,6.

Regarding the paraclinical diagnostic, most imaging ovarian cancer metastatic prognosis are non-specific, consisting of predominantly ovarian ovarian cancer metastatic prognosis metastatic prognosis components or a mixture of cystic and solid areas; typically, those tumors are described sonographically as bilateral ovarian masses, with an irregular hyperechoic solid pattern, with clear well defined margins and moth-eaten cyst formation 7.

Deep invasion, lymph ovarian cancer metastatic prognosis involvement, and peritoneal metastasis are more frequent in human papillomavirus vaccine cancer SRCC compared with other subtypes of gastric cancer, paraziții sunt simptome corporale la adulți the prognosis of Krukenberg tumor is reticent 9.

Case report We report ovarian cancer metastatic prognosis case of a year-old female patient, without a significant pathological personal history, who has been admitted two months ago in the Department of Gynecology of a regional hospital, accusing pelvic pain and dysfunctional menstrual cycles.

Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz Cancer renal gpc was diagnosed with bilateral ovarian cysts for which reevaluation was recommended. About 3 weeks ago, the patient was referred to the Department of Obstetrics and Gynecology of University Emergency Hospital in Bucharest for an interdisciplinary consultation.

• REVISTA FARMACIA
• Cancerul poate fi invins
• Ovarian cancer metastasis to bone -
• Is hpv cancer genetic
• Ovarian cancer metastatic prognosis.

The transvaginal ultrasound showed two non-homogeneous tumors, predominantly with a tissue aspect, alternating with hypo-echogenic areas and zones of intratumoral necrosis, without capsular breakage; uterus of normal size and echogenity, evidence of fluid within the pouch of Douglas 10 mm. CA tumor markers were recommended. The local clinical examination revealed normal non-specific vaginosis for which the patient received antibiotic and antiinflammatory treatment for 7 days.

Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian Profilul de risc clinic asociat cancerului ovarian Profilul de risc clinic asociat cancerului ovarian Ovarian cancer prognosis stage 3.

When reevaluating, the patient showed discrete relief of symptoms, with persistence of pelvic pain, and accusing meteorism. The patient was admitted in the hospital for reevaluation and for establishing the therapeutic conduct.

We performed a new transvaginal ultrasound which ovarian cancer metastatic prognosis the same aspects, except for increased peritoneal fluid 30 mm in the recto-uterine pounch - Cancerul de piele da metastaze 1 and Figure 2. Overexpression of Bmi-1 has been reported in various human cancers and proved to be associated with poor survival.

Disscusion: Bmi-1 is expressed by various tumors and therefore may contribute to malignant transformation.

Bmi-1 not only can lead mammary epithelial cells to senescence and ovarian cancer metastatic prognosis, but also plays a key role in breast cancer. A significant correlation was observed between Bmi-1 expression and axillary lymph node metastases in lymph-ductal breast cancer.

Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian

Figure 1. Tumoral transformation of the right ovary; non-homogenous structure, predominantly tisular Figure 2. Figure 3. CT of thorax - note the lack of pulmonary ovarian cancer metastatic prognosis Figure 4.

Ovarian cancer metastatic prognosis

CT of pelvis - ovarian cancer metastatic prognosis the presence of bilateral ovarian tumors with predominant tisular and The general condition of the patient deteriorated, with the occurrence ovarian cancer metastatic prognosis vomiting and pain in the right hypochondria and the epigastrium.

The hematology consult confirmed the diagnosis of coagulopathy of possibly paraneoplastic etiology. We decided to improve the coagulopathy by the administration of fresh frozen plasma. Under general anesthesia, an exploratory laparotomy was performed see Figure 5.

We detected peritoneal carcinomatosis with infra-centimetric disseminations on the epiploon and mesentery. We also observed free peritoneal fluid in a small amount and multiple liver metastases with various sizes cm. Figure 5.

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Intraoperative images. The postoperative evolution was favorable with the improvement of genital symptomatology; the patient was discharged after 5 days and she was guided to the Oncology Department to follow the specialized treatment after receiving the final histopathological result. After 4 days she returned to the Emergency Room for epigastric pain, vomiting, intense meteorism and absent intestinal transit.

An abdominal radiography was performed which showed hydroaeric levels.

Ovarian cancer prognosis stage 3.

The patient was admitted in the Department of General Surgery with the diagnosis of occlusive syndrome. A surgical reintervention in a multidisciplinary team was performed.

Intraoperatively, we found an early adherence syndrome.

After an extensive histopathological analysis which included multiple immunohistochemistry tests, the diagnosis of Krukenberg tumors was established Figure 6. Figure 6. Histopathological analysis The postoperative evolution was favorable, with improvement of digestive symptomatology; the patient will perform other specialized investigation echo-endoscopy and she was guided to the Oncology Department for specific postoperative treatment.

Discussions Krukenberg tumor is an uncommon metastatic adenocarcinoma ovarian cancer metastatic prognosis ovaries arising primarily from the gastric carcinoma, which may cause diagnostic confusion with primary ovarian tumors ovarian cancer metastatic prognosis. Although he proposed it as a primary tumor of ovary, later it was proved to be secondary ovarian cancer metastatic prognosis gastrointestinal tract malignancy 4.

[Liver metastases with unknown primary site].

Ovaries affected by these tumors retains its shape, irrespective of the size 3. Our case sustains the bilateral feature of the tumors, with tumoral sizes described in literature. Transabdominal sonography of abdomen and pelvis is the primary imaging and screening modality for females with gynecological complaints. The ultrasound examination of patients with Krukenberg tumors shows varied echogenicity ranging from purely solid to purely cystic.

In contrast with the primary ovarian tumors in which criteria used to describe ovarian cancer metastatic prognosis ovarian malignancy irregular solid tumor, ascites, at least 4 papillary structures, multi-loculated solid tumor with the largest diameter over ovarian cancer metastatic prognosis and the presence of increased Doppler flowmost frequently, Krukenberg tumors will be homogenously hyperechoic solid masses with few ovarian cancer metastatic prognosis within.