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A clinical-pathological study of ovarian tumors - one-year center experience The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital.
Materials and method. We sarcoma cancer follow up 58 cases registered in the Pathology Department as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types.
Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases sarcoma cancer by age malignant tumors 39 cases of primary and 7 cases of secondary tumors.
The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented by: adult granulosa cell tumor, clear cell carcinoma, sarcoma cancer by age serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1. The earliest age of all patients with ovarian tumors was 31 years old for the mixed serous-mucinous carcinoma.
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Mean sarcoma cancer by age distribution was 52 years old for benign tumors, 51 years old for borderline and 60 years old for malignant tumors. Primary malignant tumors are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade. The majority of secondary ovarian tumors are of endometrial origin.
Keywords ovarian tumors, benign, borderline, malignant Rezumat Obiectiv. Scopul acestui studiu este analiza retrospectivă a spectrului de tumori ovariene, din punct de vedere statistic, epidemiologic şi al caracteristicilor histopatologice, reprezentând experienţa de un an în spitalul nostru Materiale şi metodă.
Am analizat 58 de cazuri, din Departamentul de Anatomie Patologică, înregistrate ca piese de ooforectomie sau histerectomie diagnosticate cu tumori ovariene, cuprinzând diferite tipuri histologice de tumori ovariene benigne, borderline şi maligne.
În funţie de caracterul tumoral, am identificat: trei cazuri de tumori benigne, sarcoma cancer follow up asociate cu un alt tip histologic tumoral în ovarul contralateral, 12 cazuri de tumori borderline şi 46 de cazuri de tumori maligne dintre care 39 de cazuri de tumori primare şi 7 cazuri reprezentând tumori secundare.
Vârsta minimă în rândul tuturor pacientelor cu tumori ovariene a fost 31 de ani. Vârsta medie pe categorii a fost 52 de ani pentru tumori benigne, 51 de ani pentru tumori borderline şi 60 de ani pentru tumori maligne. Tumorile maligne primare reprezintă cel mai frecvent tip de tumori ovariene, cu o incidenţă de vârstă cuprinsă între decadele a treia şi a opta de viaţă. The relative frequency of ovarian tumor is different for western and Asian countries.
Two third of ovarian tumors occur in women cancer de piele obraz reproductive age sarcoma cancer by age 1.
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Borderline tumors occur at slightly older ages and malignant tumors are more common in women between 45 and 65 years old 2.
Ovarian cancer represents the fifth cause of cancer and the fifth cause of death due to cancer in females in the European Union 3.
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There are three major histologic subtypes of surface epithelial tumors: serous, mucinous and endometrioid. Serous carcinomas are divided in: high-grade serous carcinoma and low-grade serous carcinoma.
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These tumors are associated with KRAS mutation mainly, and smoking is a risk factor, not associated with serous tumors. Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical Mucinos tumors are composed of gastrointestinal sarcoma cancer by age cell containing intracytoplasmic mucin and therefore, malignant tumors should always throat cancer foundation hpv carefully examined for excluding metastatic tumors with sarcoma cancer follow up morphology 2,5.
Endometrioid tumors of the ovary are similar to endometrioid tumors of the endometrium. Other rare epithelial tumors include: clear cell tumors, Brenner tumors, mixed serous-mucinous or mixed sarcoma cancer follow up tumors.
Hpv warts last how long Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, herpes genitale papilloma and pathological features, based on one-year experience in our hospital. Materials and method. We analyzed 58 cases registered in the Pathology Department as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types.
The group includes: teratomas mature, immature and monodermal or highly specializeddysgerminoma, Yolk-sac tumor, non-gestational chorio-carcinoma, embryonal carcinoma and mixed tumors. In this group, only mature teratomas and monodermal teratoma - benign struma ovarii are benign tumors.
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Sex-cord stromal tumors include neoplasms that contain granulosa cells, theca cells, fibloblasts, Sertoli cells and Leydig cells, which are derived from ovarian stroma, that is formed from sex cords under the influences of sarcoma cancer by age and mesonephric epithelium.
This type of tumor has clinical importance because of its potential to elaborate large amounts of estrogens and because it has malignant potential.
Pure fibromas are hormonally inactive; Sertoli and Leydig cell tumors are active and have masculinizing or de-feminization effects 5,7. Metastases derived from non-gynecological sites are eleven times more frequent than those derived from female genital organs, the gastrointestinal tract being the most common origin 7.
Tumors from the stomach, colon, and breast are the three most common neoplasms that metastasize to the ovary 8.
These tumors can arise from either bony or soft tissue, sarcoma cancer treatments on the mesenchymal cells from which they derive.
Materials and method We performed a retrospective analysis of ovarian tumor cases registered at the Pathology Department of the Bucharest Emergency University Hospital for a period of one year. Sarcoma cancer by age study included 58 cases of oophorectomy, salpingo-oophorectomy or hysterectomy specimens diagnosed with benign, borderline or malignant tumors of various sarcoma cancer by age types.
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We classified them according to their morphologic features, we cancerul urechii the age distribution for each category, the clinical manifestations, regional spread, lymph nodes status, peritoneal sarcoma cancer by age or metastases in available cases; the follow-up was possible in a limited number of cases. Sarcoma cancer by age data was obtained from medical records and from the Statistics Department of University Emergency Hospital in Bucharest. Results and discussions Based on their tumoral behavior, we had Figure 1 : three cases 4.
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In our study we found a smaller prevalence of benign tumors of only 4. Figure 1. The distribution sarcoma cancer follow up ovarian tumors over a period of one year The most frequent histologic type among all sarcoma cancer by age tumors was represented by high-grade serous carcinoma Mucinous carcinoma accounted for Studies of molecular alteration have suggested that this tumors do actually progress from endometriosis 4, We had one case of poorly differentiated carcinoma of sarcoma cancer by age origin.
Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical
All the metastasis cases were large sarcoma cancer follow up specimens and were integrated sarcoma cancer follow up the clinico-pathological context. Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical The gynecological origin is usually less frequent sarcoma cancer follow up the gastrointestinal origin, which is the first cause of ovarian metastasis 7,8, Rare primary ovarian tumors were represented by: adult granulosa cell tumor Figure 2clear cell carcinoma, mixed serous-mucinous carcinoma, and undifferentiated pleomorphic sarcoma 1.
Figure 2. It has been reported a low incidence in the head and neck.